History of Tashkent Medical Academy dates back to 1919, when in April 13, 1919, it was decided to open a medical faculty of Turkestan State University. In 1931, the medical faculty was renamed into a medical institute called as Tashkent State Medical Institute. In 1935, the Tashkent Medical Institute was known as the Central Asian Medical Institute. The institute experienced consistent positive developmental changes and over a period of time emerged as a leading Medical Institute of Central Asia attracting a large number of local and international students. By the end of 1980, the institute had 1,042 faculty members, including 6 academicians, 24 Uzbek doctors, 90 doctors of medical sciences, professors, 207 candidates of medical sciences, associate professors, students. During this period, the Institute improved the educational, methodological, scientific, state and international relations. The Institute established cooperation with the leading medical institutions in Hungary, Germany, Poland and Russia.

First and Second Tashkent State Medical Institute

By decision of the Cabinet of Ministers of the Republic in 1990, two medical institutes were established on the basis of the old and new buildings of Tashmi in Tashkent: the First Tashkent State Medical Institute and the Second Tashkent State Medical Institute.

Tashkent Medical Academy

To improve the quality of training highly qualified medical personnel & the effectiveness of the educational process necessary to meet the needs of modern education and create a material and technical base, enriched with new content based on the latest educational technologies for future professional medical practice in teaching special skills on the basis of the abolished First and Second Tashkent State Medical Institutes by the Decree of the President of the Republic of Uzbekistan No.UP-3629 dated July 19, 2005, the Tashkent Medical Academy was established.

Termez branch of Tashkent medical academy was established by the Decree of the Cabinet of Ministers of the Republic of Uzbekistan No. 172 of March 5, 2018 based on the order given by the President of the Republic of Uzbekistan Sh.M.Mirziyoyev during his visit to the Surkhandarya region on January 19-20, 2018.